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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Team

Maria Teresa Salcedo Allende

Maria Teresa Salcedo Allende

Senior researcher
Translational Molecular Pathology
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Vicente Peg Camara

Vicente Peg Camara

Main researcher
Translational Molecular Pathology
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Elena Antima Martinez Saez

Elena Antima Martinez Saez

Translational Molecular Pathology
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Irene Sansano Valero

Irene Sansano Valero

Translational Molecular Pathology
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Jessica Camacho Soriano

Jessica Camacho Soriano

Research technician
Translational Molecular Pathology
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Jordi Temprana Salvador

Jordi Temprana Salvador

Research technician
Translational Molecular Pathology
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Maria Teresa Salcedo Allende

Maria Teresa Salcedo Allende

Senior researcher
Translational Molecular Pathology
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Vicente Peg Camara

Vicente Peg Camara

Main researcher
Translational Molecular Pathology
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Elena Antima Martinez Saez

Elena Antima Martinez Saez

Translational Molecular Pathology
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Irene Sansano Valero

Irene Sansano Valero

Translational Molecular Pathology
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Jessica Camacho Soriano

Jessica Camacho Soriano

Research technician
Translational Molecular Pathology
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Jordi Temprana Salvador

Jordi Temprana Salvador

Research technician
Translational Molecular Pathology
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Research lines

Exercise capacity, peripheral muscle dysfunction and genotype in adults with cystic fibrosis.

To study the degree and types of skeletal muscle involvement in CF patients who present exercise intolerance and its relationship with the genotype.

To determine the relationship between the type and/or degree of skeletal muscle involvement by histologic and mitochondrial respiratory chain function study, and the CF genotype.

Correlation study between exercise capacity, pulmonary function and genotype.


IP: -

Expression analysis and functional elucidation of connexins and pannexins in relation to human cancer progression and malignancy.

Connexins and pannexins are structural units of gap junctions permitting direct intercellular communication. Deregulation of gap junctions is a frequent feature of carcinogenesis. We are characterizing the expression level of a variety of connexins and pannexins in primary and metastatic human tumours. In vitro we are studying how these proteins affect features related to the degree of malignancy such as migration, invasion and resistance to hypoxia.  In connexin-deficient cell lines we are over-expressing specific wild-type or truncated forms of connexins and pannexins using retroviral constructs recently generated. In cell lines expressing high levels of specific connexins, we knockdown the expression levels using established lentiviral shRNA strategies. We aim to correlate connexin expression and cell communication with malignancy using a variety of well characterized assays with particular focus on colony formation, migration, invasion, epithelial-to-mesenchymal transition, changes in tumour stem cell populations, and hypoxia and drug resistance. The aim of the study is to: 1) Identify any significant correlation between the expression of various gap junction proteins and the malignancy, prognosis, chemo-resistance and overall survival in a variety of cancers 2) Gain mechanistic insight and identify direct functional roles of connexins and pannexins during tumour progression. 

IP: Trond Aasen

Genomic transcriptional profile analysis in proliferative inflammatory atrophy (PIA) as a possible precursor of human prostate cancer

To analyse transcriptional profiles of normal, PIA (proliferative inflammatory atrophy), PIN (prostatic intraepithelial neoplasia)  and tumoral prostate using microarrays of selected tumoral tissue of prostatectomy specimens, in order to characterize  gene expression modifications in prostate cancer versus PIN and PIA.

To analyse the biological response on tumoral / non-tumoral and co-culture them with monocytes in order to study transcriptional profile changes.

From all the data obtained, overexpressed / underexpressed genes are being identified and      validated. Stromal and inflammatory genes also will be explored for their potential use as early markers for prostatic cancer and their ability to identify PIA as a precursor lesion.

(Prostate Research Traslational Unit.)


IP: Inés de Torres Ramirez

Identification of molecular targets associated with tumor progression and therapy resistance in colorectal carcinoma.

Studying in colorectal cancer mechanisms of action of the central signal transduction pathways, identify potential molecular alterations that can be used as therapeutic targets and characterize the degree of genetic inestability.

IP: Santiago Ramon y Cajal Agüeras

Projects

Precision Endometriosis Research: Integrating Molecular Classification, In Vitro Modeling, and Personalized Therapeutic Strategies

IP: Eva Colas Ortega
Collaborators: Elena Suarez Salvador, Francesc Xavier Serra Marin, Carina Masferrer Ferragutcasas, Anna Ruano Lopez, Josep Castellví Vives, Sonia Monreal Clua, Raquel Delgado Gil
Funding agency: Fundació La Marató de TV3
Funding: 200000
Reference: 202407-10
Duration: 20/02/2025 - 19/02/2028

Búsqueda de firmas proteómicas y dianas terapéuticas en el cáncer de ovario seroso de alto grado avanzado resistente a platino

IP: Antonio Gil Moreno
Collaborators: Vicente Bebia Conesa, Francesc Xavier Serra Marin, Marta Rebull Santamaria, Martina Angeles Fite, Ana Luzarraga Aznar, Melissa Bradbury Lobato, Beatriz Villafranca Magdalena, Melek Denizli, Lourdes Elena Salazar Huayna, Lourdes Elena Salazar Huayna
Funding agency: Instituto de Salud Carlos III
Funding: 196250
Reference: PI24/01509
Duration: 01/01/2025 - 31/12/2027

Establecimiento de una estrategia combinada en carcinoma escamoso de cabeza y cuello (HNSCC): una herramienta eficaz para superar los tumores quimiorresistentes.

IP: Matilde Lleonart Pajarin
Collaborators: Yoelsis Garcia Mayea, Juan Lorente Guerrero, Josep Castellví Vives, Marina Bataller Fernández, Pablo Sanchez Sancho, Almudena Sanchez Garcia, Juan Fernando Fuentes Cabrera, Juan Fernando Fuentes Cabrera
Funding agency: Instituto de Salud Carlos III
Funding: 240000
Reference: PI24/00630
Duration: 01/01/2025 - 31/12/2027

NANORESCAN

IP: Matilde Lleonart Pajarin
Collaborators: David Virós Porcuna, Josep Castellví Vives, Marina Bataller Fernández, Almudena Sanchez Garcia, Juan Fernando Fuentes Cabrera, Juan Fernando Fuentes Cabrera
Funding agency: Instituto de Salud Carlos III
Funding: 318750
Reference:  AC24/00057
Duration: 01/01/2025 - 31/12/2027

Publications

Targeted Next-Generation Sequencing in Succinate Dehydrogenase-Deficient GI Stromal Tumor Identifies Actionable Alterations in the PI3K/mTOR Pathway.

PMID: 39787462
Journal: JCO Precision Oncology
Year: 2025
Reference: JCO Precis Oncol. 2025 Jan;9:e2400497. doi: 10.1200/PO-24-00497. Epub 2025 Jan 9.
Impact factor:
Publication type: Paper in international publication
Authors: Cicala, Carlo Maria; Fernandez-Suarez, Paula; Gomez-Peregrina, David; Gonzalez, Macarena; Gros, Luis; Landolfi, Stefania; Matito, Judit; Perez-Albert, Paula; Quindos, Maria; Romero-Lozano, Paula et al.
DOI: 10.1200/PO-24-00497

Head and Neck Cancer in Fanconi Anemia: Report of 11 Cases and a Systematic Review.

PMID: 39941721
Journal: Cancers
Year: 2025
Reference: Cancers (Basel). 2025 Jan 22;17(3):349. doi: 10.3390/cancers17030349.
Impact factor:
Publication type: Paper in international publication
Authors: Balmana-Gelpi, Judith; Bescos-Atin, Coro; Brana-Garcia, Irene; Carrasco-Lopez, Estela; de Pablo Garcia-Cuenca, Alba; Granado-Carrasco, Raquel; Lorente-Guerrero, Juan; Pujol-Pina, Rosa; Rofin-Fontanet, Pau; Temprana-Salvador, Jordi et al.
DOI: 10.3390/cancers17030349

DNA Methylation Dynamics and Prognostic Implications in Metastatic Differentiated Thyroid Cancer.

PMID: 40045915
Journal: THYROID
Year: 2025
Reference: Thyroid. 2025 Mar 6. doi: 10.1089/thy.2024.0303.
Impact factor:
Publication type: Paper in international publication
Authors: Capdevila, Jaume; Carrato, Cristina; Gil, Joan; Gonzalez, Lorena; Hernandez-Losa, Javier; Hernando, Jorge; Iglesias, Carmela; Jorda, Mireia; Klein Hesselink, Esther N; Links, Thera P et al.
DOI: 10.1089/thy.2024.0303

Effectiveness of electrocautery, topical cidofovir and topical sinecatechins for the Treatment of Anal High-grade Squamous Intraepithelial Lesions in Persons with HIV: an open-label, randomized controlled trial.

PMID: 40036375
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2025
Reference: Clin Infect Dis. 2025 Feb 27:ciaf086. doi: 10.1093/cid/ciaf086.
Impact factor:
Publication type: Paper in international publication
Authors: Burgos, Joaquin; Campany, David; Curran, Adria; Descalzo, Vicente; Dinares, Carme; Falco, Vicenc; Garcia, Jorge; Hernadez-Losa, Javier; Landolfi, Stefania; Navarro, Jordi et al.
DOI: 10.1093/cid/ciaf086

Co-expression of Twist and Snai1: predictor of poor prognosis and biomarker of treatment resistance in untreated prostate cancer.

PMID: 38281235
Journal: MOLECULAR BIOLOGY REPORTS
Year: 2024
Reference: Mol Biol Rep. 2024 Jan 28;51(1):226. doi: 10.1007/s11033-023-09167-w.
Impact factor:
Publication type: Paper in international publication
Authors: Blel, Ahlem; de Haro, Rosa Somoza Lopez; Derouiche, Amine; Hernandez-Losa, Javier; Moline, Teresa; Ouerhani, Slah; Rammeh, Soumaya; Said, Rahma; Zouari, Skander et al.
DOI: 10.1007/s11033-023-09167-w

Clinical application of the HM-1000 image processing for HER2 fluorescence in situ hybridization signal quantification in breast cancer.

PMID: 38360676
Journal: Diagnostic Pathology
Year: 2024
Reference: Diagn Pathol. 2024 Feb 15;19(1):32. doi: 10.1186/s13000-024-01455-8.
Impact factor:
Publication type: Paper in international publication
Authors: Cajal, Santiago Ramon Y; Moline, Teresa; Peg, Vicente; Roig, Miquel; Saruta, Yuko et al.
DOI: 10.1186/s13000-024-01455-8

An insight into the diagnostic, prognostic, and taxanes resistance of double zinc finger and homeodomain factor's expression in naive prostate cancer.

PMID: 38476644
Journal: 3 Biotech
Year: 2024
Reference: 3 Biotech. 2024 Apr;14(4):106. doi: 10.1007/s13205-024-03941-8. Epub 2024 Mar 10.
Impact factor:
Publication type: Paper in international publication
Authors: Blel, Ahlem; de Haro, Rosa Somoza Lopez; Derouiche, Amine; Hernandez-Losa, Javier; Jenni, Rim; Moline, Teresa; Ouerhani, Slah; Rammeh, Soumaya; Said, Rahma; Zouari, Skander et al.
DOI: 10.1007/s13205-024-03941-8

RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis.

PMID: 38523777
Journal: iScience
Year: 2024
Reference: iScience. 2024 Mar 1;27(4):109400. doi: 10.1016/j.isci.2024.109400. eCollection 2024 Apr 19.
Impact factor:
Publication type: Paper in international publication
Authors: Anguita, Estefania; Arango, Diego; Bea, Laia; Bilic, Josipa; Brotons, Bruno; Carton-Garcia, Fernando; Dopeso, Higinio; Farre, Ricard; Hernandez-Losa, Javier; Jing, Li et al.
DOI: 10.1016/j.isci.2024.109400

Liver steatosis induces portal hypertension regardless of fibrosis in patients with NAFLD: A proof of concept case report.

PMID: 36478872
Journal: JHEP Reports
Year: 2023
Reference: JHEP Rep. 2022 Oct 29;5(1):100618. doi: 10.1016/j.jhepr.2022.100618. eCollection 2023 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Barbera, Aurora; Genesca, Joan; Martell, Maria; Pericas, Juan M; Rivera-Esteban, Jesus; Salcedo, Maria Teresa et al.
DOI: 10.1016/j.jhepr.2022.100618

Chronic progressive external ophthalmoplegia plus syndrome due to Homozygous Missense Variant in TOP3A gene.

PMID: 36544354
Journal: CLINICAL GENETICS
Year: 2023
Reference: Clin Genet. 2023 Apr;103(4):492-494. doi: 10.1111/cge.14287. Epub 2022 Dec 28.
Impact factor:
Publication type: Letter whit IF
Authors: Codina-Sola, Marta; Garcia-Arumi, Elena; Juntas-Morales, Raul; Llaurado, Arnau; Lopez-Diego, Veronica; Martinez-Saez, Elena; Restrepo-Vera, Juan Luis; Rovira-Moreno, Eulalia; Salvado, Maria; Sanchez-Tejerina, Daniel et al.
DOI: 10.1111/cge.14287

Occult metastases of oral maxillary squamous cell carcinoma: Systematic review and meta-analysis.

PMID: 36515647
Journal: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Year: 2023
Reference: Head Neck. 2023 Mar;45(3):733-744. doi: 10.1002/hed.27276. Epub 2022 Dec 14.
Impact factor:
Publication type: Review in international publication
Authors: Alberola-Ferranti, Margarita; Bescos-Atin, Coro; de la Fuente, Carlos; Mis-Castell, David; Pamias-Romero, Jorge; Prat-Valero, Nil; Pujol-Pina, Rosa; Saez-Barba, Manel et al.
DOI: 10.1002/hed.27276

The doors remain open.

PMID: 36512371
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2023
Reference: Eur Heart J Cardiovasc Imaging. 2023 Jan 23;24(2):e33. doi: 10.1093/ehjci/jeac241.
Impact factor:
Publication type: Letter or abstract
Authors: Crespo, Eva Maria Pueo; Diz, Fernando Worner; Izurieta, Carlos Eduardo; Landolfi, Stefania; Ordas, Jara Gayan et al.
DOI: 10.1093/ehjci/jeac241

Cytology Smears: An Enhanced Alternative Method for Colorectal Cancer pN Stage-A Multicentre Study.

PMID: 36551559
Journal: Cancers
Year: 2022
Reference: Cancers (Basel). 2022 Dec 9;14(24):6072. doi: 10.3390/cancers14246072.
Impact factor:
Publication type: Paper in international publication
Authors: Archilla, Ivan; Balaguer, Francesc; Camps, Jordi; Castells, Antoni; Chic, Nuria; Concha, Angel; Cuatrecasas, Miriam; Diaz-Mercedes, Sherley; Lahoz, Sara; Landolfi, Stefania et al.
DOI: 10.3390/cancers14246072

Risk Factors, Radiological and Clinical Outcomes in Subclinical and Clinical Pituitary Apoplexy.

PMID: 36555904
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Dec 8;11(24):7288. doi: 10.3390/jcm11247288.
Impact factor:
Publication type: Paper in international publication
Authors: Biagetti, Betina; Casteras, Anna; Chaachou-Charradi, Anas; Cicuendez, Marta; Cordero Asanza, Esteban; Costa, Pilar; Hernandez, Irene; Martinez-Saez, Elena; Ng-Wong, Yiken Karelys; Rojano-Toimil, Alba et al.
DOI: 10.3390/jcm11247288

A combination of molecular and clinical parameters provides a new strategy for high-grade serous ovarian cancer patient management.

PMID: 36544142
Journal: Journal of Translational Medicine
Year: 2022
Reference: J Transl Med. 2022 Dec 21;20(1):611. doi: 10.1186/s12967-022-03816-7.
Impact factor:
Publication type: Paper in international publication
Authors: Borras, Eva; Bradbury, Melissa; Castellvi, Josep; Gil-Moreno, Antonio; Perez-Benavente, Assumpcio; Sabido, Eduard; Sanchez-Iglesias, Jose Luis; Santamaria, Anna; Vilar, Marta et al.
DOI: 10.1186/s12967-022-03816-7

The Presence of ANCA in IgA Crescentic Nephropathy Does Not Lead to Worse Prognosis with Intensive Rescue Treatment.

PMID: 36498699
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Nov 30;11(23):7122. doi: 10.3390/jcm11237122.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Bermejo, Sheila; Bestard, Oriol; Bolufer, Monica; Bury, Roxana; Castaneda, Zaira; Gabaldon, Alejandra; Lopez-Martinez, Marina; Ramos, Natalia; Sanz-Martinez, Maria Teresa et al.
DOI: 10.3390/jcm11237122

When Is Sentinel Node Biopsy Indicated in High-Risk Ductal Carcinoma in situ? Four Hundred Sixty-Eight Cases from Three Institutions.

PMID: 35087365
Journal: Breast Care
Year: 2021
Reference: Breast Care (Basel). 2021 Dec;16(6):630-636. doi: 10.1159/000514849. Epub 2021 Mar 30.
Impact factor:
Publication type: Paper in international publication
Authors: Acosta, Juan; Argacha, Paula; Cortadellas, Tomás; Gil-Moreno, Antonio; Gomez, Margarita; Gonzalez-Farré, Xavier; Jurado, Judith; Luna, Miguel; Martinez, Milagros; Peg, Vicente et al.
DOI: 10.1159/000514849

Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-B and AMPK1/mTOR Pathways.

PMID: 34944673
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Dec 7;9(12). pii: biomedicines9121857. doi: 10.3390/biomedicines9121857.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Sole, Cristina et al.
DOI: 10.3390/biomedicines9121857

Ultrasound criteria (EU-TIRADS) to identify thyroid nodule malignancy risk in adolescents. Correlation with cyto-histological findings.

PMID: 34924161
Journal: Endocrinologia Diabetes y Nutricion
Year: 2021
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2021 Dec;68(10):728-734. doi: 10.1016/j.endien.2020.11.006. Epub 2021 Dec 8.
Impact factor:
Publication type: Paper in international publication
Authors: Arciniegas Vallejo, Larry; Campos-Martorell, Ariadna; Clemente Leon, Maria; Coma Munoz, Ana; Guillen Burrieza, Gabriela; Iglesias Felip, Carmela; Planes-Conangla, Marina; Sabado Alvarez, Constantino; Vega Amenabar, Elizabeth; Yeste Fernandez, Diego et al.
DOI: 10.1016/j.endien.2020.11.006

Epstein-Barr Virus+ B Cells in Breast Cancer Immune Response: A Case Report.

PMID: 34868006
Journal: Frontiers in Immunology
Year: 2021
Reference: Front Immunol. 2021 Nov 16;12:761798. doi: 10.3389/fimmu.2021.761798. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Aran, Andrea; Arribas, Joaquin; Arribas, Yago A; Bernado, Cristina; Carrascal, Montserrat; Cortes, Javier; Marti, Merce; Molina, Elisa; Peg, Vicente; Perez, Jose et al.
DOI: 10.3389/fimmu.2021.761798

Correction to: Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model.

PMID: 33336303
Journal: European radiology experimental
Year: 2020
Reference: Eur Radiol Exp. 2020 Dec 17;4(1):69. doi: 10.1186/s41747-020-00202-0.
Impact factor:
Publication type: Letter or abstract
Authors: Baleriola, Mario Marotta; Cabello, Alex Claveria; Camacho, Jose Raul Herance; Castell-Conesa, Joan; de la Calle Vargas, Elena; Garcia, Vanessa Venegas; Leon, Daniel Garcia; Munoz, Paola Contreras; Pages, Roso Mares; Paun, Bruno et al.
DOI: 10.1186/s41747-020-00202-0

MicroRNAs in Several Cutaneous Autoimmune Diseases: Psoriasis, Cutaneous Lupus Erythematosus and Atopic Dermatitis.

PMID: 33321931
Journal: Cells
Year: 2020
Reference: Cells. 2020 Dec 10;9(12). pii: cells9122656. doi: 10.3390/cells9122656.
Impact factor:
Publication type: Review in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Sole, Cristina et al.
DOI: 10.3390/cells9122656

Five microRNAs in Serum Are Able to Differentiate Breast Cancer Patients From Healthy Individuals.

PMID: 33224883
Journal: Frontiers in Oncology
Year: 2020
Reference: Front Oncol. 2020 Nov 3;10:586268. doi: 10.3389/fonc.2020.586268. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Altes, Anna; Artola, Mireia; Barragan, Nieves; Benavente, Sergi; Castellvi, Josep; Cortes, Javier; Espinosa-Bravo, Martin; Feliciano, Andrea; Garcia-Mayea, Yoelsis; Gonzalez, Lucila et al.
DOI: 10.3389/fonc.2020.586268

TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance.

PMID: 33167355
Journal: Cancers
Year: 2020
Reference: Cancers (Basel). 2020 Nov 5;12(11). pii: cancers12113269. doi: 10.3390/cancers12113269.
Impact factor:
Publication type: Paper in international publication
Authors: Allonca, Eva; Benavente, Sergi; Carballo, Laia; Castellvi, Josep; Garcia-Mayea, Yoelsis; Garcia-Pedrero, Juana M; LLeonart, Matilde E; Lorente, Juan; Mir, Cristina; Rodrigo, Juan P et al.
DOI: 10.3390/cancers12113269

Validation of Cell-Free DNA Collection Tubes for Determination of EGFR Mutation Status in Liquid Biopsy from NSCLC Patients.

PMID: 32699985
Journal: Oncology and therapy
Year: 2019
Reference: Oncol Ther. 2019 Dec;7(2):131-139. doi: 10.1007/s40487-019-00099-9. Epub 2019 Aug 19.
Impact factor:
Publication type: Paper in international publication
Authors: Cordoba, Juan Felipe; Hernandez-Losa, Javier; Maestu, Inmaculada; Ramon Y Cajal, Santiago; Sanchez, Alfredo; Sansano, Irene; Sese, Marta; Somoza, Rosa; Ureste, Maria Martin; Venturas, Griselda et al.
DOI: 10.1007/s40487-019-00099-9

Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH.

PMID: 31882668
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Dec 27;9(1):20183. doi: 10.1038/s41598-019-56366-2.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Barbera, Aurora; Bravo, Miren; Fernandez-Iglesias, Anabel; Genesca, Joan; Gil, Mar; Hide, Diana; Martell, Maria; Raurell, Imma; Salcedo, Maria Teresa et al.
DOI: 10.1038/s41598-019-56366-2

Reply to: "Mitochondrial Parkinsonism due to SPG7/Paraplegin variants with secondary mtDNA depletion".

PMID: 31845766
Journal: MOVEMENT DISORDERS
Year: 2019
Reference: Mov Disord. 2019 Dec;34(12):1932-1933. doi: 10.1002/mds.27899.
Impact factor:
Publication type: Letter or abstract
Authors: Alvarez, Victoria; Barahona-Hernando, Raul; Catalina, Irene; De la Casa-Fages, Beatriz; Fernandez-Eulate, Gorka; Fernandez-Pelayo, Uxoa; Gamez, Josep; Garcia-Barcina, Maria; Grandas, Francisco; Holt, Ian et al.
DOI: 10.1002/mds.27899

Asymmetric distribution of glucose transporter mRNA provides a growth advantage in yeast.

PMID: 30910878
Journal: EMBO JOURNAL
Year: 2019
Reference: EMBO J. 2019 May 15;38(10). pii: embj.2018100373. doi: 10.15252/embj.2018100373. Epub 2019 Mar 25.
Impact factor:
Publication type: Paper in international publication
Authors: Ehrenfeuchter, Nikolaus; Fucile, Geoffrey; Hummer, Stefan; Mittal, Nitish; Spang, Anne; Stahl, Timo et al.
DOI: 10.15252/embj.2018100373

Clinical study of a patient with congenital myotonic dystrophy reveals chylothorax as neonatal presentation of the disease

PMID: NOPMID0074
Journal: CASE REPORTS IN PERINATAL MEDICINE
Year: 2018
Reference: Case Reports in Perinatal Medicine. 2018 Mar 28;7(1). doi: 10.1515/crpm-2017-0025
Impact factor:
Publication type: Paper in international publication
Authors: Castillo, Felix; Cueto-Gonzalez, Ana; Lines, Marcos; Martinez-Saez, Elena; Tizzano, Eduardo; Valenzuela, Irene et al.
DOI: 10.1515/crpm-2017-0025

Phenformin-induced mitochondrial dysfunction sensitizes hepatocellular carcinoma for dual inhibition of mTOR.

PMID: 32177313
Journal: ANNALS OF ONCOLOGY
Year: 2018
Reference: Ann Oncol. 2018 Jun;29 Suppl 5:v91. doi: 10.1093/annonc/mdy151.323. Epub 2020 Jan 7.
Impact factor:
Publication type: Letter or abstract
Authors: Cajal, S R Y; Ge, X; Hernandez-Alvarez, M; Hernandez-Losa, J; Kozma, S; Mercer, C; Thomas, G; Thomas, H; Veiga, S; Zorzano, A et al.
DOI: 10.1093/annonc/mdy151.323

Author Correction: STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis.

PMID: 29921958
Journal: NATURE MEDICINE
Year: 2018
Reference: Nat Med. 2018 Sep;24(9):1481. doi: 10.1038/s41591-018-0108-5.
Impact factor:
Publication type: Letter or abstract
Authors: Bertero, Luca; Bindeman, Wendy; Blanco-Aparicio, Carmen; Bosch-Barrera, Joaquim; Doglio, Laura; Fustero-Torre, Coral; Hernandez-Encinas, Elena; Hernandez-Lain, Aurelio; Martinez, Liliana; Martinez, Lola et al.
DOI: 10.1038/s41591-018-0108-5

Eukaryotic initiation factor 4F-sidestepping resistance mechanisms arising from expression heterogeneity.

PMID: 29169064
Journal: CURRENT OPINION IN GENETICS & DEVELOPMENT
Year: 2018
Reference: Curr Opin Genet Dev. 2018 Feb;48:89-96. doi: 10.1016/j.gde.2017.11.002. Epub 2017 Nov 21.
Impact factor:
Publication type: Review in national publication
Authors: Cajal, Santiago Ramon Y; Chu, Jennifer; Pelletier, Jerry; Sonenberg, Nahum et al.
DOI: 10.1016/j.gde.2017.11.002

Corrigendum: Pio del Rio-Hortega: A Visionary in the Pathology of Central Nervous System Tumors.

PMID: 28381992
Journal: Frontiers in Neuroanatomy
Year: 2017
Reference: Front Neuroanat. 2017 Apr 3;11:27. doi: 10.3389/fnana.2017.00027. eCollection 2017.
Impact factor:
Publication type: Letter or abstract
Authors: Ramon Y Cajal Agueras, Santiago et al.
DOI: 10.3389/fnana.2017.00027

Prevalence and clinical association of MET gene overexpression and amplification in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape project.

PMID: 28838386
Journal: LUNG CANCER
Year: 2017
Reference: Lung Cancer. 2017 Sep;111:143-149. doi: 10.1016/j.lungcan.2017.07.021. Epub 2017 Jul 22.
Impact factor:
Publication type: Paper in international publication
Authors: Bubendorf, Lukas; Cheney, Richard; Dafni, Urania; Das-Gupta, Ashis; Finn, Stephen P; Geiger, Thomas R; Hager, Henrik; Kammler, Roswitha; Kerr, Keith M; Marchetti, Antonio et al.
DOI: 10.1016/j.lungcan.2017.07.021

Epileptic features and survival in glioblastomas presenting with seizures.

PMID: 28073027
Journal: EPILEPSY RESEARCH
Year: 2017
Reference: Epilepsy Res. 2017 Feb;130:1-6. doi: 10.1016/j.eplepsyres.2016.12.013. Epub 2016 Dec 26.
Impact factor:
Publication type: Paper in international publication
Authors: Aizpurua, Miren; Auger, Cristina; Maldonado, Xavier; Martinez-Ricarte, Francisco; Martinez-Saez, Elena; Quintana, Manuel; Rodon, Jordi; Salas-Puig, Javier; Santamarina, Estevo; Sarria-Estrada, Silvana et al.
DOI: 10.1016/j.eplepsyres.2016.12.013

Intraoperative assessment of sentinel lymph node by one-step nucleic acid amplification in breast cancer patients after neoadjuvant treatment reduces the need for a second surgery for axillary lymph node dissection.

PMID: 27810698
Journal: BREAST
Year: 2017
Reference: Breast. 2017 Feb;31:40-45. doi: 10.1016/j.breast.2016.10.002. Epub 2016 Nov 2.
Impact factor:
Publication type: Paper in international publication
Authors: Diaz-Botero, Sebastian; Duenas Rodriguez, Basilio; Espinosa-Bravo, Martin; Luque Lopez, Carolina; Navarro-Cecilia, Joaquin; Peg, Vicente; Ramos Boyero, Manuel; Ramos Grande, Teresa; Ruano Perez, Ricardo; Rubio, Isabel T et al.
DOI: 10.1016/j.breast.2016.10.002

Pio del Rio-Hortega: A Pioneer in the Pathology of Central Nervous System Tumors.

PMID: 26973470
Journal: Frontiers in Neuroanatomy
Year: 2016
Reference: Front Neuroanat. 2016 Mar 1;10:13. doi: 10.3389/fnana.2016.00013. eCollection 2016.
Impact factor:
Publication type: Review in international publication
Authors: Ramon Y Cajal Agueras, Santiago et al.
DOI: 10.3389/fnana.2016.00013

Diagnostic imaging in spontaneous rupture of a thoracic duct cyst in the mediastinum.

PMID: 27117300
Journal: Radiologia
Year: 2016
Reference: Radiologia. 2016 Nov - Dec;58(6):491-495. doi: 10.1016/j.rx.2016.03.002. Epub 2016 Apr 23.
Impact factor:
Publication type: Paper in national publication
Authors: Pallisa, E; Persiva, O; Sansano, I; Varona Porres, D et al.
DOI: 10.1016/j.rx.2016.03.002

Analysis of expression of PTEN/PI3K pathway and programmed cell death ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM).

PMID: 27133741
Journal: LUNG CANCER
Year: 2016
Reference: Lung Cancer. 2016 Jun;96:1-6. doi: 10.1016/j.lungcan.2016.03.001. Epub 2016 Mar 10.
Impact factor:
Publication type: Paper in international publication
Authors: Cedres, S; Enguita, A; Felip, E; Martinez-Marti, A; Montoro, M A; Navarro-Mendivil, A; Pardo-Aranda, N; Ponce-Aix, S; Sansano, I; Zugazagoitia, J et al.
DOI: 10.1016/j.lungcan.2016.03.001

A patient with suspected non-ST elevation acute myocardial infarction and remarkably high brain natriuretic peptide levels.

PMID: 26440456
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2016
Reference: Int J Cardiol. 2016 Jan 1;202:485-7. doi: 10.1016/j.ijcard.2015.09.048. Epub 2015 Sep 25.
Impact factor:
Publication type: Paper in international publication
Authors: Baneras, Jordi; Barrabes, Jose A; Buera, Irene; Dorado, David Garcia; Fort, Joan; Ibernon, Meritxell; Marti, Gerard; Oristrell, Gerard; Sansano, Irene et al.
DOI: 10.1016/j.ijcard.2015.09.048

Clinical features, course and prognosis of idiopathic membranous nephropathy depending on the presence of antibodies against M-type phospholipase A2 receptor.

PMID: 26306972
Journal: NEFROLOGIA
Year: 2015
Reference: Nefrologia. 2015;35(5):479-86. doi: 10.1016/j.nefro.2015.05.026. Epub 2015 Jul 7.
Impact factor:
Publication type: Paper in national publication
Authors: Agraz Pamplona, Irene; Carnicer Caceres, Clara; Jatem Escalante, Elias; Martin-Gomez, M Adoracion; Ostos Roldan, Helena; Salcedo Allende, Maria Teresa; Segarra Medrano, Alfons et al.
DOI: 10.1016/j.nefro.2015.05.026

[Appendicular actinomycosis as a cause of ileocecal mass in children: Case report].

PMID: 27775308
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2015
Reference: Cir Pediatr. 2015 Jul 20;28(3):137-141.
Impact factor:
Publication type: Paper in national publication
Authors: Coma Munoz, A; Fernandez Castilla, M; Ferreres Pinas, J C; Guillen Burrieza, G; Martin Nalda, A; Salazar Villacorta, A et al.
DOI:

Acute Antibody-Mediated Rejection as Cause of Late Liver Allograft Failure: A Case Report.

PMID: 26707330
Journal: TRANSPL P
Year: 2015
Reference: Transplant Proc. 2015 Dec;47(10):3016-9. doi: 10.1016/j.transproceed.2015.10.036.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, I; Caralt, M; Castells, L; Charco, R; Dopazo, C; Lazaro, J L; Montero, A; Salcedo, M T; Sapisochin, G; Vellalta, G et al.
DOI: 10.1016/j.transproceed.2015.10.036

Long-term follow-up of dose-adjusted EPOCH plus rituximab (DA-EPOCH-R) in untreated patients with poor prognosis large B-cell lymphoma. A phase II study conducted by the Spanish PETHEMA Group.

PMID: 25521006
Journal: BRIT J HAEMATOL
Year: 2015
Reference: Br J Haematol. 2015 Apr;169(2):188-98. doi: 10.1111/bjh.13273. Epub 2014 Dec 18.
Impact factor:
Publication type: Paper in international publication
Authors: Batlle, Ana; Bergua, Juan; Carnicero, Fernando; Castellvi, Josep; de Villambrosia, Sonia Gonzalez; Ferrando-Lamana, Lucia; Gallur, Laura; Garcia-Marco, Jose A; Lopez, Andres; Lopez, Luis A et al.
DOI: 10.1111/bjh.13273

Expression of Wilms' tumor gene (WT1) is associated with survival in malignant pleural mesothelioma.

PMID: 24323466
Journal: Clinical & Translational Oncology
Year: 2014
Reference: Clin Transl Oncol. 2014 Sep;16(9):776-82. doi: 10.1007/s12094-013-1146-6. Epub 2013 Dec 10.
Impact factor:
Publication type: Paper in international publication
Authors: Cedres, S; Farinas, L; Felip, E; Gabaldon, A; Martinez, A; Martinez, P; Montero, M A; Navarro, A; Ramon Y Cajal, S; Torrejon, D et al.
DOI: 10.1007/s12094-013-1146-6

Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project.

PMID: 25071109
Journal: JOURNAL OF CLINICAL ONCOLOGY
Year: 2014
Reference: J Clin Oncol. 2014 Sep 1;32(25):2780-7. doi: 10.1200/JCO.2013.54.5921. Epub 2014 Jul 28.
Impact factor:
Publication type: Paper in international publication
Authors: Blackhall, Fiona H; Bubendorf, Lukas; Cheney, Richard; Dafni, Urania; de Jong, Jeroen; Dooms, Christoph; Hager, Henrik; Hernandez Losa, Javier; Hernandez-Losa, Javier; Kerr, Keith M et al.
DOI: 10.1200/JCO.2013.54.5921

SPROUTY2 is a beta-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer.

PMID: 23624922
Journal: ONCOGENE
Year: 2014
Reference: Oncogene. 2014 Apr 10;33(15):1975-85. doi: 10.1038/onc.2013.140. Epub 2013 Apr 29.
Impact factor:
Publication type: Paper in international publication
Authors: Barbachano, A; Chicote, I; Huelsken, J; Irmisch, A; Landolfi, S; Munoz, A; Ordonez-Moran, P; Palmer, H G; Tabernero, J; Tenbaum, S et al.
DOI: 10.1038/onc.2013.140

Establishing the origin of metastatic deposits in the setting of multiple primary malignancies: the role of massively parallel sequencing.

PMID: 24220311
Journal: Molecular Oncology
Year: 2014
Reference: Mol Oncol. 2014 Feb;8(1):150-8. doi: 10.1016/j.molonc.2013.10.006. Epub 2013 Oct 31.
Impact factor:
Publication type: Paper in international publication
Authors: Berger, Michael F; Bidard, Francois-Clement; Cortes, Javier; De Mattos-Arruda, Leticia; Jungbluth, Achim A; Ng, Charlotte K Y; Nuciforo, Paolo; Peg, Vicente; Reis-Filho, Jorge S; Seoane, Joan et al.
DOI: 10.1016/j.molonc.2013.10.006

[Clinico-pathological and molecular aspects of diagnostic and prognostic value in gliomas].

PMID: 23359078
Journal: Revista de neurologia
Year: 2013
Reference: Rev Neurol. 2013 Feb 1;56(3):161-70.
Impact factor:
Publication type: Paper in national publication
Authors: Jimenez-Leon, P; Martinez, E; Ortega-Aznar, A; Romero-Vidal, F J et al.
DOI:

A dominant-negative N-terminal fragment of HER2 frequently expressed in breast cancers.

PMID: 22641219
Journal: ONCOGENE
Year: 2013
Reference: Oncogene. 2013 Mar 14;32(11):1452-9. doi: 10.1038/onc.2012.152. Epub 2012 May 28.
Impact factor:
Publication type: Paper in international publication
Authors: Arribas, J; Baselga, J; Bech-Serra, J J; Bernado Morales, C; Canals, F; Ibrahim, Y H; Morancho, B; Pandiella, A; Parra-Palau, J L; Peg, V et al.
DOI: 10.1038/onc.2012.152

Dual regulation of Myc by Abl.

PMID: 23318434
Journal: ONCOGENE
Year: 2013
Reference: Oncogene. 2013 Nov 7;32(45):5261-71. doi: 10.1038/onc.2012.621. Epub 2013 Jan 14.
Impact factor:
Publication type: Paper in international publication
Authors: Amati, B; Bianchi, M; Conacci-Sorrell, M; Doglioni, C; Doni, M; Eisenman, R N; Faga, G; Losa, J H; Mazzarol, G; Peg, V et al.
DOI: 10.1038/onc.2012.621

ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor.

PMID: 23292912
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2013
Reference: Int J Cancer. 2013 Jul;133(1):235-46. doi: 10.1002/ijc.28009. Epub 2013 Feb 12.
Impact factor:
Publication type: Paper in international publication
Authors: Casanovas, O; Castillo-Avila, W; Condom, E; Garcia Del Muro, X; Germa, J R; Graupera, M; Hernandez-Losa, J; Juliachs, M; Pandiella, A; Piulats, J M et al.
DOI: 10.1002/ijc.28009

p38alpha limits the contribution of MAP17 to cancer progression in breast tumors.

PMID: 22266858
Journal: ONCOGENE
Year: 2012
Reference: Oncogene. 2012 Oct 11;31(41):4447-59. doi: 10.1038/onc.2011.619. Epub 2012 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Blanco-Aparicio, C; Carnero, A; Ferrer, I; Guijarro, M V; Marin, J J; Munoz-Galvan, S; Ramon y Cajal, S; Roncador, G; Vergel, M et al.
DOI: 10.1038/onc.2011.619

Sub-frontal approach in the treatment of esthesioneuroblastoma

PMID: 91000018
Journal: Revista Española de Cirugía Oral y Maxilofacial
Year: 2012
Reference: Rev Esp Cirug Oral y Maxilofac vol.36 no.4 Barcelona oct./dic. 2014
Impact factor:
Publication type: Paper in national publication
Authors: Gutierrez Santamaria, Javier; Lliset Rosa; Malet Hernández, Daniel; Mogedas Vegara, Alfonso; Ramón y Cajal Agüeras, Santiago; Sahuquillo Barris, Joan et al.
DOI: 10.1016/j.maxilo.2012.09.007

[Translation and validation of the Spanish version of the EAT-10 (Eating Assessment Tool-10) for the screening of dysphagia].

PMID: 23588456
Journal: Nutricion Hospitalaria
Year: 2012
Reference: Nutr Hosp. 2012 Nov-Dec;27(6):2048-54. doi: 10.3305/nh.2012.27.6.6100.
Impact factor:
Publication type: Paper in national publication
Authors: Araujo, K; Barcons, N; Burgos, R; Cardenas, G; Perez-Portabella, C; Puiggros, C; Romagosa, A; Sarto, B; Segurola, H; Vazquez, C et al.
DOI: 10.3305/nh.2012.27.6.6100

A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells.

PMID: 22657348
Journal: BIOCHEMICAL JOURNAL
Year: 2012
Reference: Biochem J. 2012 Aug 15;446(1):9-21. doi: 10.1042/BJ20111144.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Banks, Lawrence; Edward, Michael; Graham, Sheila V; Hernandez-Lopez, Hegel; Hodgins, Malcolm B; Macdonald, Alasdair I; Massimi, Paola; Roberts, Sally; Sun, Peng et al.
DOI: 10.1042/BJ20111144

Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC.

PMID: 22164285
Journal: PLoS One
Year: 2011
Reference: PLoS One. 2011;6(12):e28406. doi: 10.1371/journal.pone.0028406. Epub 2011 Dec 2.
Impact factor:
Publication type: Paper in international publication
Authors: Callejas-Valera, Juan L; de la Cruz-Morcillo, Miguel A; Fernandez-Aramburo, Antonio; Galan-Moya, Eva M; Hernadez Losa, Javier; Llanos Valero, Maria; Melgar-Rojas, Pedro; Ramon y Cajal, Santiago; Salcedo, Mayte; Sanchez-Prieto, Ricardo et al.
DOI: 10.1371/journal.pone.0028406

[Hyper-reactive malarial splenomegaly in a 9 year-old Equatorial Guinean child].

PMID: 21419729
Journal: ANALES DE PEDIATRIA
Year: 2011
Reference: An Pediatr (Barc). 2011 Jul;75(1):80-1. Epub 2011 Mar 17.
Impact factor:
Publication type: Letter or abstract
Authors: Coll Usandizaga, F; Garcia Pena, M P; Moraga Llop, F A; Tobena Rue, M; Toran Fuentes, N et al.
DOI: 10.1016/j.anpedi.2011.01.037

B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.

PMID: 22197976
Journal: NATURE IMMUNOLOGY
Year: 2011
Reference: Nat Immunol. 2011 Dec 25;13(2):170-80. doi: 10.1038/ni.2194.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/ni.2194

Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma.

PMID: 22131884
Journal: NEOPLASIA
Year: 2011
Reference: Neoplasia. 2011 Nov;13(11):1093-100.
Impact factor:
Publication type: Paper in international publication
Authors: Adimoolam, Shanthi; Allende, Maria Teresa Salcedo; Buggy, Joseph J; Evan, Gerard I; Kortlever, Roderik; Monclus, Helena Allende; Soucek, Laura; Swigart, Lamorna Brown et al.
DOI:

Remodeling of the fetal collecting duct epithelium.

PMID: 20035053
Journal: AMERICAN JOURNAL OF PATHOLOGY
Year: 2010
Reference: Am J Pathol. 2010 Feb;176(2):630-7. Epub 2009 Dec 24.
Impact factor:
Publication type: Paper in international publication
Authors: Hiatt, Michael J; Ivanova, Larissa; Matsell, Douglas G; Tarantal, Alice F; Toran, Nuria et al.
DOI: 10.2353/ajpath.2010.090389

Differences in the Form of Presentation between Papillary Microcarcinomas and Papillary Carcinomas of Larger Size.

PMID: 21209704
Journal: Journal of thyroid research
Year: 2010
Reference: J Thyroid Res. 2010 Dec 14;2011:639156.
Impact factor:
Publication type: Letter or abstract
Authors: Baena, Juan Antonio; Castellvi, Josep; Mesa, Jordi; Monroy, Gabriela; Obiols, Gabriel; Zafon, Carles et al.
DOI: 10.4061/2011/639156

Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer.

PMID: 21167064
Journal: Journal of Translational Medicine
Year: 2010
Reference: J Transl Med. 2010 Dec 18;8:135. doi: 10.1186/1479-5876-8-135.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/1479-5876-8-135

TGF-beta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma.

PMID: 21156287
Journal: CANCER CELL
Year: 2010
Reference: Cancer Cell. 2010 Dec 14;18(6):655-68.
Impact factor:
Publication type: Paper in international publication
Authors: Anido, Judit; Barba, Ignasi; Baselga, Jose; Carmona, Maria A; Cuartas, Isabel; Folch, Gerard; Garcia-Dorado, David; Gonzalez-Junca, Alba; Lahn, Michael M; Martinez-Ricarte, Francisco et al.
DOI: 10.1016/j.ccr.2010.10.023

Clinico-pathological discrepancies in the diagnosis of causes of maternal death in sub-Saharan Africa: retrospective analysis.

PMID: 19243215
Journal: PLOS MEDICINE
Year: 2009
Reference: PLoS Med. 2009 Feb 24;6(2):e1000036.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Pedro L; Balasch, Juan; Bombi, Josep A; Carrilho, Carla; Ismail, Mamudo R; Machungo, Fernanda; Menendez, Clara; Ordi, Jaume; Osman, Nafissa; Romagosa, Cleofe et al.
DOI: 10.1371/journal.pmed.1000036

p16 INK4a immunostaining identifies occult CIN lesions in HPV-positive women.

PMID: 19047902
Journal: INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
Year: 2009
Reference: Int J Gynecol Pathol. 2009 Jan;28(1):90-7.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Immaculada; del Pino, Marta; Garcia, Sonia; Landolfi, Stefania; Ordi, Jaume; Quinto, Llorenc; Torne, Aureli et al.
DOI: 10.1097/PGP.0b013e31817e9ac5

Primary monophasic synovial sarcoma of the duodenum confirmed by cytogenetic analysis with demonstration of t(X;18): a case report.

PMID: 19337641
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2009
Reference: J Gastrointestin Liver Dis. 2009 Mar;18(1):89-93.
Impact factor:
Publication type: Letter or abstract
Authors: Company Campins, Maria Margarita; Dolz, Carlos; Garcia-Bonafe, Magdalena; Huguet, Pere; Morales, Rafael; Vilella, Angels et al.
DOI:

MMPs/TIMPs and inflammatory signalling deregulation in human incisional hernia tissues.

PMID: 19397782
Journal: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Year: 2009
Reference: J Cell Mol Med. 2009 Nov-Dec;13(11-12):4432-43.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1582-4934.2008.00637.x

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes.

PMID: 18931654
Journal: NATURE BIOTECHNOLOGY
Year: 2008
Reference: Nat Biotechnol. 2008 Nov;26(11):1276-84. doi: 10.1038/nbt.1503. Epub 2008 Oct 17.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Barrero, Maria J; Bilic, Josipa; Boue, Stephanie; Consiglio, Antonella; Edel, Michael; Garreta, Elena; Gonzalez, Federico; Izpisua Belmonte, Juan Carlos; Pekarik, Vladimir et al.
DOI: 10.1038/nbt.1503

Tissue-specific effects of wild-type and mutant connexin 31: a role in neurite outgrowth.

PMID: 17142249
Journal: HUMAN MOLECULAR GENETICS
Year: 2007
Reference: Hum Mol Genet. 2007 Jan 15;16(2):165-72. doi: 10.1093/hmg/ddl452. Epub 2006 Dec 1.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Kelsell, David P; McElwaine, Suzanne; Unsworth, Harriet C et al.
DOI: 10.1093/hmg/ddl452

Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia.

PMID: 16091133
Journal:
Year: 2005
Reference: Mol Cancer. 2005 Aug 9;4(1):31. doi: 10.1186/1476-4598-4-31.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Edward, Mike; Graham, Sheila V; Hodgins, Malcolm B et al.
DOI: 10.1186/1476-4598-4-31

Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis.

PMID: 15769851
Journal: JOURNAL OF CELL SCIENCE
Year: 2005
Reference: J Cell Sci. 2005 Apr 1;118(Pt 7):1505-14. doi: 10.1242/jcs.01733. Epub 2005 Mar 15.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Common, John E A; Di, Wei-Li; Gu, Yan; Kelsell, David P; O'Toole, Edel A; Zicha, Daniel et al.
DOI: 10.1242/jcs.01733

The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression.

PMID: 12970745
Journal: ONCOGENE
Year: 2003
Reference: Oncogene. 2003 Sep 11;22(39):7969-80. doi: 10.1038/sj.onc.1206709.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Edward, Michael; Graham, Sheila V; Hodgins, Malcolm B et al.
DOI: 10.1038/sj.onc.1206709

Transport and function of cx26 mutants involved in skin and deafness disorders.

PMID: 14681041
Journal:
Year: 2003
Reference: Cell Commun Adhes. 2003 Jul-Dec;10(4-6):353-8. doi: 10.1080/cac.10.4-6.353.358.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Hodgins, Malcolm; Laird, Dale W; Thomas, Tamsin et al.
DOI: 10.1080/cac.10.4-6.353.358

The effects of a mutant connexin 26 on epidermal differentiation.

PMID: 14681042
Journal:
Year: 2003
Reference: Cell Commun Adhes. 2003 Jul-Dec;10(4-6):359-64. doi: 10.1080/cac.10.4-6.359.364.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Bakirtzis, George; Bryson, Sheila; Finbow, Malcolm; Forrow, Stephen; Greenhalgh, David; Hodgins, Malcolm; Jamieson, Susan; Tetley, Laurence et al.
DOI: 10.1080/cac.10.4-6.359.364

Targeted epidermal expression of mutant Connexin 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders.

PMID: 12837696
Journal: HUMAN MOLECULAR GENETICS
Year: 2003
Reference: Hum Mol Genet. 2003 Jul 15;12(14):1737-44. doi: 10.1093/hmg/ddg183.
Impact factor:
Publication type: Paper in international publication
Authors: Aasen, Trond; Bakirtzis, George; Brown, Ken; Bryson, Sheila; Choudhry, Rukhsana; Finbow, Malcolm; Forrow, Stephen; Greenhalgh, David; Hodgins, Malcolm; Shore, Leonard et al.
DOI: 10.1093/hmg/ddg183

Thesis

Predictive value of axillary tumoral load in breast cancer by OSNA method

PhD student: Irene Sansano Valero
Director/s: Vicente Peg Camara
University: Universidad Autònoma de Barcelona
Year: 2021

Estudio patológico de biomarcadores en la angiopatía amiloide cerebral y la enfermedad de Alzheimer

PhD student: Jessica Camacho Soriano
Director/s: Maria Mar Hernandez Guillamon, Elena Antima Martinez Saez, Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2021

Biòpsia selectiva del gangli sentinella en el carcinoma papil·lar de tiroide. Anàlisi morfològica i valor de la càrrega tumoral ganglionar

PhD student: Carmela Iglesias i Felip
Director/s: Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2020

Significant roles of ITGB3 in the tumour microenvironment: EMT driver in hypoxic conditions and central axis in intercellular communication

PhD student: Pedro Fuentes Varela
Director/s: Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2020

Internal Translation of Truncated Gap Junction Proteins in Health and Disease: Generation, Regulation and Function

PhD student: Maria José Muñoz Guijarro
Director/s: Trond Aasen
University: Universidad Autònoma de Barcelona
Year: 2019

Estudio de nuevas aproximaciones terapéuticas para la regeneración neural y el tratamiento de la espina bífida mediante el uso de terapia celular durante la etapa fetal

PhD student: Alejandra Fernández Martín
Director/s: Mario Marotta Baleriola, José Luis Peiró Ibáñez
University: Universidad Autònoma de Barcelona
Year: 2017

Estudi de la via de senyalització de 4E-BP1. lmplicacions pronostiques i terapeutiques en el melanoma uveal

PhD student: Mª Carme Dinarès Fernández
Director/s: Javier Hernandez Losa, Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2017

Valoración de la expresión inmunohistoquímica en microarrays tisulares de RACK1, 4ebp1, p53 y Ki-67 en tumores colorrectales con correlación clínico patológica

PhD student: Paul Augusto Espinoza Madrid
Director/s: Miriam Cuatrecasas Freixas, Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2016

Estudio de las Vias de señalización en cáncer de ovario y de endometrio: Implicaciones en el pronóstico

PhD student: Josep Castellví Vives, Josep Castellví Vives
Director/s: Angel García Jiménez, Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2016

Trombofilia y embarazo

PhD student: Elena Antima Martinez Saez
Director/s: Amparo Santamaría Ortiz, Amparo Santamaría Ortiz
University: Universidad Autònoma de Barcelona
Year: 2016

Estudio de vías de señalización celular en astrocitomas infiltrantes difusos

PhD student: Elena Antima Martinez Saez
Director/s: Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2015

Neoplasia intraepitelial pancreática y adenocarcinoma ductal de páncreas: Estudio de factores de las vías de señalización celular y su correlación con la clínica

PhD student: Maria Teresa Salcedo Allende, Maria Teresa Salcedo Allende
Director/s: Javier Hernandez Losa, Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2015

Carga tumoral total en el ganglio centinela de pacientes con cáncer de mama en estadios iniciales

PhD student: Vicente Peg Camara, Vicente Peg Camara, Vicente Peg Camara
Director/s: Josep Lluis Parra Palau, Santiago Ramon y Cajal Agüeras, Isabel Teresa Rubio Rodríguez
University: Universidad Autònoma de Barcelona
Year: 2015

Estudio de la fosforilación de eIF4E y del factor 4E-T en situaciones de estrés celular en cáncer de mama

PhD student: Alba Martinez Diaz
Director/s: Trond Aasen , Santiago Ramon y Cajal Agüeras
University: Universidad Autònoma de Barcelona
Year: 2014

Estudio de vías de señalización en sarcomas

PhD student: César Serrano Garcia
Director/s: Joan Carles Galceran, Santiago Ramon y Cajal Agüeras, Cleofé Romagosa Pérez-Portabell
University: Universidad Autònoma de Barcelona
Year: 2014

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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