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Catàleg de models animals

Catàleg de models animals del Vall d'Hebron Barcelona Hospital Campus

Utilitza el cercador per trobar els models que necessites per a la teva investigació.

Reference Name Animal specie Strain Thematic area Specific pathology Description
AT122 Cardiac Ischemia mouse model Mice (Mus musculus) C57BL/6J Cardiovascular diseases Cardiac Ischemia
Model generated by myocardial infarction induction
AT123 Cardiac Ischemia pig model Pig (Sus scrofa) Cardiovascular diseases Cardiac Ischemia
Model generated by myocardial infarction induction
AT011 Cx43-deficiency in mice induced by 4-hydroxytamoxifen intraperitoneal administration Mice (Mus musculus) Hybrid strain C57BL6J y OlaHsd: Cx43Cre-ER(T)/fl Cardiovascular diseases Cardiac deletion of Cx43: arrhythmias and sudden death (50% after 14 days of induction)
Ablation of Cx43 expression is achieved by 4-hydroxytamoxifen (4-OHT) treatment in adult mice intraperitoneally injected once a day, for 5 consecutive days, with 3 mg of 4-OHT.
AT009 Chronic Liver Disease induced by intraperitoneal injection of thioacetamide (TAA) Rat (Rattus norvegicus) Sprague-Dawley OFA Liver Diseases Hepatic cirrhosis
Rats receive the first week a dose of 250mg/Kg IP of TAA twice a week, the following 7 weeks they receive a dose of 200mg/Kg IP twice a week, being a total of 8 weeks and 16 injections After 8 weeks of treatment at a dose of 250-200mg/kg, twice a week, all animals will develop histological features of cirrhosis
AT008 Chronic Liver Disease induced by inhalation of carbon tetrachloride (CCl4) Rat (Rattus norvegicus) Wistar Han Liver Diseases Hepatic cirrhosis
With the administration of CCl4 we produce an acute hepatitis, and with its continued administration we generate a chronic liver injury that leads to the development of cirrhosis. To speed up the model, phenobarbital is administered to water (0.3 g/L) one week before starting the hepatotoxic exposure and until the end of the experiment We will consider that the animal has developed cirrhosis with portal hypertension after 12 weeks of inhalation.
AT128 Chronic Kidney disease (CKD) model Mice (Mus musculus) CypB KO Nephrology Renal fibrosis
Model generated by unilateral uretral obstruction (UUO). The ureter is doubly ligated at the midpoint between the kidney and the bladder.
AT127 Cardiac Ischemia-Reperfussion rat model Rat (Rattus norvegicus) Sprague Dawley® Cardiovascular diseases Cardiac Ischemia, reperfussion
Myocardial infarction followed by reperfussion
AT126 Cardiac Ischemia-Reperfussion pig model Pig (Sus scrofa) Cardiovascular diseases Ischemia/reperfussion
Myocardial infarction followed by reperfussion
AT125 Cardiac Ischemia-Reperfussion mouse model Mice (Mus musculus) C57BL/6J Cardiovascular diseases Cardiac Ischemia, reperfussion
Myocardial infarction followed by reperfussion
AT124 Cardiac Ischemia rat model Rat (Rattus norvegicus) Sprague Dawley® Cardiovascular diseases Cardiac Ischemia
Model generated by myocardial infarction induction

Sol·licitud de models animals

Aquest catàleg s'actualitza anualment. Per informació addicional i/o sol·licitar models animals, pots posar-te en contacte amb nosaltres a catalogo.animales@vhir.org.

També podeu cercar models animals a la Plataforma ISCIII de Biomodels i Biobancs.